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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24187f67def237b7e5d2f755ca7459afe76de7fd96cac144e162a91717865f17' 
  AND token = 'F94qt9I4CtjCUFDwKt8rxyni0hvRrX7U2yNDlyIRkZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}