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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '463f70f7c37ccd93c2f94f803903ff730204a5a4f07ef75892186c2a0d800651' 
  AND token = 'DCD8HQFZmRkrOnn2/9Yr2ybJi9FL0cHWwN+kalZctJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}