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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '592147bb2312d6e2d0793f06652a01764f6907de2b9d86c06b3bd2187d6d8ca3' 
  AND token = 'bU4Wm1TI4uicQZ7SV4EM0Qytl9nlr1GfV0iYflN3Dik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}