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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57729c8a1a3e27b6a142ebb9dac94babfcc307a3b993cb21316956ff31efb390' 
  AND token = 'wacOQoFSZyPrTt3O1e/dIlTQYoG9PPs3nTn1CQB31vg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}