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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162a7d28638e7202ced6c5b633e4fefde029f53a1af32c611ade4880bd93289c' 
  AND token = 'DCpeaGJ+ecNGEvEZxkGzwLCqDZ9PWdOY4Zg9cvqFnfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}