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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19c7483aeb729416c34c627f39a375fec8c5caee91c5804f57b8268f1daead14' 
  AND token = 'XUR8LcLJcqpNf+9tune0tOzo5DXIywa+OvhTmp2A7jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}