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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5007f73521261ec2535f40351a943a9aa45883c3fad44f5b1e5b5e643e26eae' 
  AND token = 'EuwbCsg6EKiCMrbpvPnwe03LglEsmq/Z2IC21g4B5CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}