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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b10fd0ec79358de80df0ec6cf4ecbc9099e6cf2c914b4e240306919659fb560' 
  AND token = 'NLtAcZ5MV/pgTUCop+epG6GL+lthreL7445RunjehH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}