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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c15342ad9bd859273ea2663569a75017aa53c5f5b2bdd5c01c96409fd6b79c1' 
  AND token = 'TsqMyHBFu+lLZTF7G6dpo1RoQ+FI019uEy+U1f0nakU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}