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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4288c25644041a0a9a63f35026d1180eb223755b521cee6cb1b9043d0291103' 
  AND token = 'cq+sZMGp96i1HoVgqpIC45f3P6bM5tXeQ/5K7UZdIXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}