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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0bd7a0aa0ca4cf07ee1277f159bef0ab1f60f532abb65214844306e66d041350' 
  AND token = 'DDAhffkOM/VlRtxAUCE7kuzkL9VJBxAEHYOuRxs+MxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}