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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52fdc8cc3f64c01629bc76a1aa9df5898bf6268bfb05ba1e0193d59c123d74d6' 
  AND token = 'DfrxY+PZ7DMGUaDGp3YmfpKFNmVs/PCa4ot9AkGnQ9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}