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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '850f16feb681024b7a701c7fb6fda017fed62a1e835a9797f0fcc024d1ad0b3b' 
  AND token = 'E4xiW4QpVLyFxCu1h5SdLnFqgiErpvsYu6n7l2djI+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}