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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22592b801032c4f45530f4be85120b3af7340e033f617598632181485411a9b9' 
  AND token = '3aj0fQ/wI10O8XtCBK0HeZrCl8feF8MB4XuBQ2jVjnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}