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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c01146799ae8da1771e914f4fa961a672d66c7c351a7acddec2ad07681300101' 
  AND token = 'Nw3DoNcvqvj5UXnMlebcqnQA1OtKGwaAW0ru2/DHdBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}