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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac341ecbf359aa251702e7fb440eb0b5703f9a929bba62ce4440c862e34d46c' 
  AND token = 'wM3TkmBjCiN3KzAO+4QdTWhUtNLjtuzvcPfOqBgBbis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}