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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d10e02c9e5d361e682d22c68f47fbcfb211d79472fd000145ba21ce521f086' 
  AND token = '3Pr2ycH+pINztFy36qWUT3n3BIlu5KqYqWVpSLpKREo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}