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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3aa25457d5928414f5ec3a234143772e0c120c659b8130acabd396edb604646' 
  AND token = 'C2HXOD/OH9HtevZvqJkVXErTiR8i0RD5pl85yXGsMbg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}