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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7725ee46c78c74a23d58a831cbf78a212b5c8e80d07ab2dd6d0fdac9de2e6c71' 
  AND token = '1Apv4yWOXNfbhwzoMhQ8hbCoCEVkan0I/n2lZV0Sgec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}