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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f50714a3f6494b9865bbe7b268a5b46eb7c1befdc4440ba7ad36b645a742d79' 
  AND token = 'ABpFW1MJNw3NzxCIwdIEKZjK15QqgtKshqwerXO2fOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}