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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8adb470cb6f58af22486d41a3380d76e75daab428497ca3fb676a4cfac9de341' 
  AND token = '3N2qKiPHafet1AOzO+WA3UaAw0sz3HsZYH6KDBY6wPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}