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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c33a11ce5ed7316cc59f5c67966419ee012069490fdb3434d74d3ff450662d95' 
  AND token = 'C1b0MeEXmeO2TF+KPKa8B6rrMdnEd6YBTysDbToAGTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}