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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ac1f5c044cdbacde5b0d90192f74245ca79cfc50e561270385e43089e6d6527' 
  AND token = 'HVmji/P1mWrIV9x1fTkQK5OaD5QClCTrMoH3NaDw/Wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}