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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '576bacf20f4339de5283e76f915b94fbbaf08e22ce9a2b8b417021b2c69531c1' 
  AND token = 'W3RKIXq0Yyi5yw12fc1DzkDINu6psNip1WyBEklVnXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}