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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e45b7ab3be8449b374896dd2e0afcd9c1cdc41877da4020b1febe85c50d4a30b' 
  AND token = 'NbfIHZPR/a1RChxq/UkJS3ICp50bMmQ6plC53g8A2Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}