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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41fe8fd6e8c13295ea37c6a143200ec9735f6c786e21ad048d81d531dc3e5ab5' 
  AND token = 'toqo6M+zC7h9CIDLyPhOlF/nlFiqc5aHP0BmZct48G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}