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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '735dfb2d749a791e5768a512c172ff8fe99846a47ba4a1fd801cb33f4e08f479' 
  AND token = 'WL+M2N3xNTw75GzpQrIRxLHCMWYS4ZW3bC5R4ACZRZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}