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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37ec27fbd9be1a0a7d179fde7ad22ff95d710c5a566705d2d9db2e6edfdcd21' 
  AND token = 'htR6vUZjbalqgxdSLzx0AlacN1BHw3N1MAqeISaWGDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}