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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '23a0460361154b0c29016f0fd3e43d1d1c9b3634046744e2af18823b448df016' 
  AND token = 'HGSbcEJ8sHrtfETG5HjA/ujzTk0hN2igEhjYE8Qhx7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}