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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b34010d5ef6ad7929192cce14035b17f741417ffe37d9d84a9fab856457a1548' 
  AND token = 'Nk0uS4f+WcsV1ceD8fP4//qMHoZ7Hk0Cku+WrbWPQNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}