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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5983be6fec326b4faba202ff2bdfbfe1fca5952a9cd3c74c6fc377072204d21' 
  AND token = 'VBLxovfJA+lGfIrXzbHbD3bqz6+CcjEqnbqsyW+jPxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}