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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1069b7af808673708ee48b8b9495572933015483e9a3d8faf977ba70194d6f3' 
  AND token = 'Iz2OEeVRGbZ/ixkdDGsEVc16yInGg/6Ny54SlsihIVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}