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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daa0d29fde21756fff6780d29ee722cc2268c71624f016b3bb15342326ee3a53' 
  AND token = 'g/hfUFHU67TFBkZ52wrPM/WX3G+pI8tICxm2CFA1ybA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}