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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '036f00e0fa2c113266e70a75a093c45ad5dc1dd3de709d8d226275564182f248' 
  AND token = 'q6RgVuevaGCP/vuPRrGi/sgFKnG2CJe1aq4yiCEzfEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}