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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddfb7e56072a6fb222b686a6245d5a4255c5532650365696b35eed4ba1fa6975' 
  AND token = 'd0scvJPX4W3gEfdeNB8bRO1BKDkxgvWQl4lQAFGw5AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}