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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dfe56724182c7f93c403b90b01c1a2de92f022efa86ff23360adf3a76bc92ec' 
  AND token = 'YmS9qQB2CF4MoE2/EFmlYWdYX3txH13V8S/wBrbtP3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}