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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd720433aec083d8b4521db73548183141ccf8cdbe5a705660289c65f3030e441' 
  AND token = 'V/fvkh7umQ4rwUWo5I9PghdRl2pE40yAGP83X481SZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}