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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d6fee3607d6463c4aea6c2d0c72ce72ac3ebeab94c6e4317aa0e1dc1e3cb961' 
  AND token = 'MeUSlpG0shDtqW1yZniaxKIT+ZxA+diRKxNfGmfW9VM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}