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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4383395af0ce3f4353442adea06fb397190ef45f194ff8c70e35969a1c6e8096' 
  AND token = 'W2E3yk2RKFp1BpubVjJQY+EHyALJaEOcvXSxnVDD6DA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}