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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea0dc1bd74ec9dcbbd6f115a51d80512090fb1f8d39884b17539c780cb94968' 
  AND token = 'zz5rqh4uQpMLTv3aAbjiiPwDYlPBB1MxXdeJmSS4QnM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}