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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef5acd26b77a44dd00da4770dfd6c4dd1fa2d25e0acad3d5a67fd5f8bdf19618' 
  AND token = 'NTKF2viPjBjkrMNUy/9f+iEHEYJ46roglP6uf/7V0g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}