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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6ef4e517f0632b86de2376265fa1b3483f9b7c82dda1204ed5cdf541f56b825' 
  AND token = 'IBCs4QrW9WGv6ltbkb968aAONb2NVZ+uCLmVBfVgyao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}