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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7591e5f08ceabf2b3e0e6b402f3c6c73de6c36ff20c5fc903e10a58264e9a921' 
  AND token = 'Vb//O4jTiXGkviUVtyEoLhy9TLp1ZTA7aB7N5TIgJGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}