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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1990363cf8be97df60cb815b62c59ac8f7b8b61ae5ff4f05e0f15e08cb859f6d' 
  AND token = 'a9y+mo9Bw/mX1v9GbCHdcZ+qCg0uDl5V3qdweiNEAjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}