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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4df435478760ae7afb11fedfb3c1cffe2bfd4ae7e647d042218042067cb092' 
  AND token = 'yGyY/SUbjPl2P6vBYgyi6J/7RqPG/R1UFy1RJngHnEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}