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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcefc1ab308e215c85efead6034f7a2ce38e51f55b31fc8218febc36f2c6d342' 
  AND token = 'e+XjF+z9zYInYqzvW2ZZ6p0oSTzipYW/hp1Lw1rkwLk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}