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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '267e578ef660f080fcb4e0c30d0b1ec07ef72b1efaf6bdaae4908897579bbb41' 
  AND token = 'xyk7pBi7a/OgNkpKeRSSt2jtKE6OcBojzX1IVp5R3Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}