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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c8c41c17a44e3518bc2daafb44e39f249ec67e7ce36e7664ede0d6424c3d13' 
  AND token = 'qC+qCcSCLFgmXwAmMcF5M+1d6gIa/D0OTZfTgWETGLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}