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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9548b8879f51adffe8781281dc00cfb51a3b82664e40cad2f7ed84fe9b40995f' 
  AND token = '25cGwHyl+m/3EJftp3stMzom16Us99Lz9imnhfHADf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}