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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0da206e178689791991ecd776964a82b1ee4565766d267cc306e7e78a82d8fca' 
  AND token = 'CESCh4lYLzf8E9FJATbxr3spXoRhrDr25uHriP2EBwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}